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NAVIGATOR – PAST RECIPIENTS


2019

Francesca Cicchetti, PhD

Université Laval

Project title:  Targeting the blood brain barrier to treat Huntington’s disease

2018

Cheryl Arrowsmith, PhD

University of Toronto

Project title:  Structural studies of the huntingtin protein with cryo electron microscopy

2017

Stephen Ferguson, PhD

University of Ottawa

Project title:  mGluR5 as a target for the treatment of Huntington’s disease

 

Lynn Raymond, MD, PhD

University of British Columbia

Project title:  Impaired corticostriatal synaptic plasticity in HD: Investigating a role for aberrant endocannabinoid signaling

 

2016

Matthew Parsons, PhD

Memorial University

Project title:  Probing Novel Therapeutic Targets for the Treatment of Cognitive Decline in HD

 

Christopher Pearson, PhD

Hospital for Sick Children

Project title:  Modulating HD CAG repeat instability for clinical benefit

2015

Michael Haydon, MD

University of British Columbia

Project title:  Pre-clinical therapeutic evaluation of allele-specific mutant huntingtin suppression by antisense oligonucleotides

 

Blair Leavitt, MD

University of British Columbia

Project title:  The contribution of microglia and neurons to HD pathogenesis

2014

Stephen Ferguson, PhD

Western University/University of Ottawa

Project title:  Utility of mGluR5 antagonists for the treatment of HD

Rona Graham, PhD

Université de Sherbrooke

Project title:  Role of olfactory dysfunction in HD

David Stellwagen

McGill/MUHC

Project title:  TNF-mediated synaptic plasticity in Huntington’s Disease

2013

Robert Cumming

Western University

Project title:  Non-canonical activation of Nrf2 as a potential therapeutic strategy for the treatment of HD

2012

Lynn Raymond, MD, PhD

University of British Columbia

Project title:  Role of thalamic input in striatal dysfunction in a mouse model of HD

Simonetta Sipione

University of Alberta

Project title:  Therapeutic activity of novel synthetic gangliomimetic compounds in HD

David Stellwagen

MUHC research Institute

Project title:  TNF-mediated synaptic plasticity in HD

2011

Stephen Ferguson, PhD

Western University

Project title:  Role of Metabotropic Glutamate Receptors in HD

Blair Leavitt, MD

University of British Columbia

Project title:  Neuroinflammation in the YAC128 mouse model of HD

2010

Grant Hatch, PhD

University of Manitoba

Project title:  Cardiolipin genes as biomarkes of HD

Simonetta Sipione, PhD

University of Alberta

Project title:  Therapeutic use of ganglioside GM1 in HD

Ray Truant, PhD

McMaster University

Project title:  Defining toxic and protective conformations of the amino-terminus of mutant huntingtin protein at the nanometer scale by use of FLIM-FRET and HRM in live cells.

2009

Francesca Cicchetti, PhD

Université Laval

Project title:  Investigation of the Effects of Pathological Environment on Graft Survival in HD

Eileen Denovan-Wright, PhD

Dalhousie University

Project title:  Regulation of transcription in HD

Michael Hayden, MD

University of British Columbia

Project title:  The Role of HIP14-mediated Palmitoylation and Proteolysis in the Pathogenesis of HD

 

2008

Simonetta Sipione, PhD

University of Alberta

Project title:  Role of Gangliosides in HD

2006

Francesca Cicchetti, PhD

Université Laval

Project title:  In depth analysis of graft implants in a Huntington disease patient: lead into long-term graft survival, development and connectivity (integration with brain).

 

2005

Michael Hayden, MD

University of British Columbia

Project title:  Role of huntingtin Phosphorylation in the Serine 421 (pS421) Pathogenesis of HD

 

2003

Janice Braun, PhD

University of Calgary

Project title:  Association of N-Type Calcium Channels with Huntingtin (exp) and Huntington (nonexp)

Maxime Philbert

Université du Québec à Montréal

Project title:  Attention and Inference in Huntington Disease


 

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