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Research Articles

Relevant articles and research papers about the latest developments and discoveries in HD research. Please note that the majority of the below articles are papers and articles from scientific journals and are therefore not in layman's terms.  For the latest research updates in layman's terms please see Research News.

For more articles please visit the Research Archive

Huntingtin Has a Membrane Association Signal Aggregation, Nuclear Entry and Toxicity (by Ray Truant, HSC Funded Researcher)

A systematic review of the treatment studies in Huntington disease since 1990

Brain Imaging and Cognitive Dysfunction in Huntington disease

Proximity to Clinical Onset Influences Motor and Cognitive Performance in  Presymptomatic Huntington Disease Gene Carriers

Extensive neuroprotection  by choroid plexus transplants in excitotoxin lesioned monkeys

Heat shock protein 70 alters the endosome-lysosomal localization in  huntingtin

Reduced expression of  PSA-NCAM in the hippocampus and piriform cortex  of the R6/1 and R6/2  mouse models of Huntington disease

Young people's experiences of growing up in a family affected by Huntington disease

Huntington Disease: Pathological Mechanisms and Therapeutic Strategies

Huntingtin Cleavage Induced by Thrombin In Vitro

Clinical Characteristics of Childhood Onset (Juvenile) Huntington Disease: Report of 12 Patients and Review of the Literature

Managing genetic discrimination: Strategies used by individuals found to  have the Huntington disease mutation

Probability of Obsessive and Compulsive Symptoms in Huntington disease