In this short video from the 2012 HD Therapeutics Conference in Palm Springs, presenting speaker Charles Sabine highlights some of the major themes discussed at this year’s meeting and gives a sense of some Huntington disease research developments to keep an eye on. Created by CHDI Foundation.

Last October we honoured the life of former politician and Speaker of the House, the Honourable James Jerome.

Click the following link to view videos of the keynote speakers at the 25th Anniversary HDSA National Convention in Raleigh, North Carolina in June 2010.

HDSA Keynote Speaker Videos

 

The NBC News correspondent's address in 2 video files, hosted on the site of the Huntington's Disease Society of America.

Click here to watch.

CMMT: 2009 World Congress on Huntington Disease a Huge Success
With over 700 attendees from 33 countries across the globe, the 2009 World Congress on Huntington Disease (September 12- 15, 2009), was the largest annual international gathering on HD globally. This event, hosted by Drs. Michael Hayden and Blair Leavitt, both scientists at the Centre for Molecular Medicine and Therapeutics, brought some of the most prominent HD researchers, clinicians and members of the HD community from around the world to Vancouver, BC.

Read the full article...

•WCHD 2009 Nightly News: Part 1, Sunday Sept 13th
•WCHD 2009 Nightly News: Part 1, Monday Sept 14th
•WCHD 2009 Nightly News: Part 1, Tuesday Sept 15th

Nature, Nuture and Neuroscience: Exploring gene-environment interactions in Huntington's disease to search for new therapies
Anthony Hannan, Ph.D.
In order to make progress towards delaying onset in gene-positive family members, and stopping or reversing the disease in patients, we need to understand HD comprehensively, integrating knowledge at the level of molecules, cells and behaviour.  Dr. Hannan will describe how his research group has used a mouse model of HD to try to bridge this explanatory gap between the gene mutation and disease symptoms.   He will also describe how their discovery that increased levels of mental and physical activity can delay onset and progression of disease in HD mice can be used to develop new therapeutic approaches.

Dr. Hannan is an associate professor at the Howard Florey Institute, University of Melbourne, where he studies gene-environment interactions and disease mechanisms in brain disorders, with a focus on HD. Prior to that, he served as a Senior Research Scientist and University Research Lecturer in Oxford, England.

Video 1: Genetic Story of HD, HD Mice
Video 2: Testing of HD Mice
Video 3: The Mice Maze & Environmental Enrichment
Video 4: Neurogenesis & Anti-Depressants
Video 5: Environmental Factors & HD
Video 6: Question & Answer Session pt.1
Video 7: Question & Answer Session pt. 2

Click here to download Dr. Hannan's powerpoint presentation


Promising HD research: Now and in the future
Ray Truant, Ph.D.
With so many research results pouring in, it can be hard to see the Huntington's forest for the trees. Dr. Truant will enable participants to see the bigger picture and understand the drug discovery process. He will explain the lines of attack that are most likely to yield useful treatments in the foreseeable future and respond to questions.

Dr. Truant is an associate professor in the department of Biochemistry and Biomedical Sciences at McMaster University. He has authored several high-level reviews of HD research and is the architect of promising research into brain cell death which has identified new targets for HD drugs. In 2001, Dr Truant won the CIHR "New Scientist" award. He currently chairs HSC's Research Council.

Video 1: What Causes HD
Video 2: Reversing HD in Mice
Video 3: siRNA Therapy
Video 4: HD Biomarkers
Video 5: Polyglutamine Diseases
Video 6: Kinase Inhibitors
Video 7: Live Imaging of HD Cells
Video 8: Live Imaging of HD Cells & Cell Stress
Video 9: Drug Discovery Pipeline
Video 10: Drug Discovery Pipeline pt. 2
Video 11: CHDI & HD Research Funding
Video 12: HD Affects the World